Antonio Giordano, MD, PhD

Antonio Giordano, MD, PhD

Medical Oncology

Top Doctor Award Badge

Languages Spoken

Italian

Contact Information

Office Phone Number

617-632-3800

Fax

617-632-1930

Appointments

617-632-2175

Biography

Antonio Giordano, MD, PhD

Dr. Giordano completed his medical school and oncology fellowship at University of Naples Federico II in Italy in 2004 and 2009, respectively. His passion for research was the motivation behind his pursuit of a PhD program in medical oncology and immunology at the Second University of Naples and participating in the exchange program with The University of Texas MD Anderson Cancer Center. During the four years spent as faculty at MD Anderson, he consolidated his solid foundation in breast clinical oncology, transitional and basic science research, and has made tremendous contributions to the field of breast cancer biology and circulating biomarkers. His work was recognized by two very prestigious awards for young investigators, the 2012 AACR-Bristol-Myers Squibb Oncology Fellowship in Clinical Cancer Research and the 2012 ASCO Young Investigator Award. He subsequently worked as faculty at MUSC in Charleston, SC from 2016 to 2020, where he successfully completed the NCI K12 Paul Calabresi Career Development for Clinical & Translational Oncology Program.  

In 2020, Dr. Giordano joined the staff of Dana-Farber Cancer Institute, where he is a medical oncologist and clinical investigator in the Breast Oncology Center.  

Dr. Giordano serves as the clinical director of the Center for Cancer Therapeutic Innovation and the Breast Cancer Pathways Medical Director at Dana Farber. His area of excellence is investigation, translational science, and phase 1 clinical trials for patients with metastatic breast cancer that is resistant to standard therapeutic options. His research focus in on mechanisms of resistance to CDK4/6 inhibitors, cell cycle, and trial innovations in the HR+/HER2- metastatic space. 

 

Researcher

Physician

Clinical Director Center for Cancer Therapeutic Innovations (Early Drug Development)
Medical Director Breast Cancer Pathway
Senior Physician
Assistant Professor of Medicine, Harvard Medical School

Clinical Interests

Circulating Biomarkers, Drug Development, Immune-Oncology

Diseases Treated

Board Certification

  • Internal Medicine, 2016
  • Medical Oncology, 2019

Fellowship

  • University of Naples Federico II

Residency

  • Medical University of South Carolina

Medical School

  • University of Naples Federico II

Recent Awards

  • Scholarship award for podium presentation at ASCO Annual Meeting, 2010
  • Scholarship award for poster discussion session SABCS, 2010
  • ASCO/AACR Clinical Research Workshop Scholarship, 2011
  • 2012 AACR-Bristol-Myers Squibb Oncology Fellowship in Clinical Cancer Research
  • ASCO Young Investigator Award, 2012
  • NCI K12 Paul Calabresi Career Development for Clinical & Translational Oncology Program, 2019

Research

    Antonio Giordano, MD, PhD is a breast medical oncologist at Dana-Farber Cancer Institute. During his PhD program in medical oncology and immunology, he studied the biology and clinical relevance of circulating tumor cells (CTC) and cancer-initiating stem cells in breast cancer. During the four years spent as faculty at MD Anderson, he consolidated his solid foundation in breast clinical oncology, transitional and basic science research, and has made tremendous contributions to the field of breast cancer biology. He received two prestigious grant awards, the 2012 AACR-Bristol-Myers Squibb Oncology fellowship in clinical cancer research and the 2012 ASCO Young Investigator Award, for a project on single-nucleus DNA sequencing to investigate CTC origin in breast cancer patients. In 2016 he joined the Division of Hematology/Oncology at MUSC in Charleston SC and received the K12 Paul Calabresi & Translational Oncology Training Program Award with a laboratory project on triple-negative breast cancer and Polo-like kinase 1. Dr. Giordano was awarded the METAVIVOR Early Career Investigator Award to support a phase 1 clinical trial with a Plk1 inhibitor in metastatic breast cancer patients with TP53 mutation. At Dana-Farber Cancer Institute he is a Clinical Investigator in the Breast Oncology Center and Center for Cancer Therapeutic Innovation. His main area of interest is HR+ metastatic breast cancer and cell cycle inhibition. He is the Principal Investigator on many clinical trials, including selective CDK4 and CDK2 inhibitors, KAT6A inhibitors, PIK3CA mutant selective inhibitors, and new antibody drug conjugates. Dr. Giordano believes that oncology is a diversified discipline and to be involved in research to beat cancer would be his prerogative as a translational oncologist. 

    Locations

    Location Avtar

    Dana-Farber Cancer Institute

    450 Brookline Avenue Boston, MA 02215
    Get Directions
    Dana-Farber Chestnut Hill Building

    Dana-Farber Cancer Institute - Chestnut Hill

    300 Boylston Street Chestnut Hill, MA 02467
    Get Directions

    Dana-Farber Cancer Institute

    Location Avtar

    Dana-Farber Cancer Institute

    450 Brookline Avenue Boston, MA 02215
    Get Direction
    42.3374, -71.1083

    Dana-Farber Cancer Institute - Chestnut Hill

    Dana-Farber Chestnut Hill Building

    Dana-Farber Cancer Institute - Chestnut Hill

    300 Boylston Street Chestnut Hill, MA 02467
    Get Direction
    42.3192, -71.1798

    Ratings and Comments

    Antonio Giordano, MD, PhD

    About Our Ratings

    Physician Star Rating Comment Block